Monday 12 March 2012

History of coffee > Health & Pharmacology



Health & Pharmacology

A cup of coffee, depending on the strength, may contain some 20-100mg of caffeine. Some types of coffee may also contain significant amounts of the B-vitamin niacin, although this nutrient is of course readily available from other foods as well.

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Effect of coffee on body


There are two types of physiologically active substances in coffee; The first type include caffeine,  which is involved in the enhancement of psychic well-being, chlorogenic acid, lipids, and the substances that are formed at roasting such as trigonelline and some volatile contituents that are responsible for creating the unique flavour of coffee. The second type include exogenous contamination from aromatic hydrocarbons, mycotoxins, and pecticides.
The most physiologically stimulating substance with most effect on the body is caffeine, with the rest of the substances having minimal effects.
Caffeine has been shown to stimulate respiration, an action mediated through the release of hormones, dopamine and serotonin.  

From: Coffee: Physiology by R.J. Clarke and R. Macrae

Other reported effects of coffeine are listed below:
1- Stimulation of blood circulation (i.e. heart) and central nervous system
2- Increasing the fatty acid content of blood, making it more ‘slugy’
3- Increasing stomach aciditiy and iritating the lining of the stomach
4- Relaxing the intestinal muscles, thereby making digestion less effective
5- Increasing urination upon overoncsumption, due to the diuretic effect
6- Increasing the intensity of brain activity, resulting in a temporary feeling of alertness in short term, followed by feelings of fatigue.
7- Overconsumtion causes overstimulation of the nervous system, resulting in adverse effects on the length and the quality of sleep.
8- Overconsumption has been reported to decrease bone density in women.
9-Heavy consumption has been associated with “caffeine nerves”, characterized by shaking hands, palitations, and wobbliness in the legs.
10- Heavy consumption causes hyperactivity of adrenal glands, causing the release of glucose into the blood stream. Although this results in a temporary lift, pressure is imposed on the pancreas to produce insulin to decrease the blood sugar content. The final effect could be an overeactive pancreas that produce too much insulin, thus mopping up too much glucose from the blood, resulting in chronic tiredness.
It is important to consider that the above effects vary with individuals.


Advantages & disadvantages

Effects on health and diseases

Should we avoid drinking coffee?

Though caffeine has some benefits in relation to exercise performance, risks have been documented. Most problems seem evident with very high consumption. The American Heart Association says that moderate coffee drinking (one or two cups per day) does not seem to be harmful for most people. As with everything else, moderation is the key to healthy caffeine consumption. Further research is needed to clearly determine whether the performance-enhancing benefits of caffeine outweigh the potential risks.
Resource:
http://www.overcaffeinated.org/effects-of-caffeine-on-the-body.php

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